Chemicals Policy & Science Initiative LCSP
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PBT Profiler and other EPA Initiatives to Promote Substitution

The PBT Profiler is an online screening tool that predicts a chemical's potential to persist in the environment, bio-concentrate in animals, and be toxic, properties which cause concern for human health and the environment. Basing its assessment on a chemical's structure, the PBT Profiler determines if a chemical is expected to exceed the PBT criteria under EPA's New Chemicals Program and/or Toxic Release Inventory (TRI). The PBT Profiler can also tell the user if the chemical belongs to a category that is known to present human health concerns as described in EPA's Chemicals Category Report.
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